Get a steamer, fill that sucker up, and start spraying every seam on your mattress, your bed frames, in power sockets, under the baseboards along the walls in the affected room, and then lay down diatomaceous earth everywhere. Then start throwing any clothing left around your mattress into the dryer, run them for at least 30 minutes, or at least until they're almost too hot to handle. Got curtains near your bed? Check those fuckers, and even if they look clean, toss them into the dryer too.
But what if they come back? Instead of diatomaceous earth, start laying minefields of Cimexa, even bedbugs that have adapted to DE can't handle it; it's synthetic silicate, and it dries them the fuck out very quickly.https://www.amazon.com/CimeXa-Insecticide-ounces-bottle-Rockwell/dp/B0085HRWI8
After all this horribly inconvenient, time consuming and obnoxious shit, periodically spot check previously affected areas for the next month, and make sure that any laundry or linens stay far away from the old hot spots.
Also, don't bother fucking around with bedbug sprays, the stuff that's available to consumers is 99% dogshit.