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As opposed to characters originally fleshed out in full blown fiction piece (think Drizzle the Dual showing up in your adventure).
I always found module/notable location characters to tend to fall into dour, two-dimensional issue resolution mindset when roleplayed by the DMs, be it someone else or even me. After you finally help them get their plot rocks off they 9 times out of 10 evaporate like a weak fart. Did you encounter any particular character descriptions or descriptive formulas in general that set up actually interesting personalities? Something that maybe fosters inner conflict and the like. Staying power is also something I'm interested in. If a character has a motive to interface with adventurers more than when he's in need. Ever had a dude stick organically for most of the wider campaign? I sure didn't.
Additionally how do you rate premade NPCs vs character generators. I find most of the time just getting a couple hooks for a nobody works better than someone sweating off quareter page entry for me.