>>37366842A bad NTFS commit in the wrong place can render windows inoperable, say a bad commit to one of the registry hives of windows, for example.
Chances are extremely low, but it does happen, and if the computer wasn't restarted in a day, system restore starts taking snapshots of a messed up registry.
And the error, as I said, was in the [graphical mode initialization] stage of the boot process, so you will be unable to access safe mode.